KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYLK3
All Species:
10.3
Human Site:
T351
Identified Species:
32.38
UniProt:
Q32MK0
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q32MK0
NP_872299.2
819
88393
T351
T
P
G
E
M
L
M
T
G
R
G
S
L
G
P
Chimpanzee
Pan troglodytes
XP_527218
388
44535
Rhesus Macaque
Macaca mulatta
XP_001113601
819
88691
T351
T
P
G
E
M
L
V
T
R
R
G
S
L
G
P
Dog
Lupus familis
XP_532569
1037
110071
T558
T
P
G
E
L
L
V
T
R
A
A
G
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UIZ8
795
86353
T347
T
P
G
E
L
L
E
T
Q
S
G
S
P
I
G
Rat
Rattus norvegicus
P20689
610
65798
T179
I
I
S
C
S
E
K
T
L
A
M
K
P
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521045
729
77615
E294
E
T
P
G
S
E
A
E
P
E
A
D
P
G
P
Chicken
Gallus gallus
P11799
1906
210428
D1110
L
Q
C
R
I
S
S
D
P
P
A
S
V
S
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.5
94.5
45.3
N.A.
69.2
37.2
N.A.
49.4
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.4
95.9
53.3
N.A.
76.5
50.6
N.A.
58.1
29.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
53.3
N.A.
53.3
6.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
93.3
66.6
N.A.
60
6.6
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
13
0
0
25
38
0
0
0
0
% A
% Cys:
0
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% D
% Glu:
13
0
0
50
0
25
13
13
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
13
0
0
0
0
13
0
38
13
0
38
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
13
0
0
13
0
0
0
0
0
0
0
0
13
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
0
% K
% Leu:
13
0
0
0
25
50
0
0
13
0
0
0
38
13
0
% L
% Met:
0
0
0
0
25
0
13
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
13
0
0
0
0
0
25
13
0
0
38
0
50
% P
% Gln:
0
13
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
0
0
25
25
0
0
0
0
0
% R
% Ser:
0
0
13
0
25
13
13
0
0
13
0
50
0
25
13
% S
% Thr:
50
13
0
0
0
0
0
63
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
25
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _